Journal: Journal of Clinical Medicine
Article Title: Two-Year Switzerland Cohort Results from a Global Observational Study Investigating Proactive Dosing with Intravitreal Aflibercept 2 mg in Neovascular Age-Related Macular Degeneration
doi: 10.3390/jcm14072370
Figure Lengend Snippet: Visual acuity outcomes from baseline to Months 12 and 24 in patients with nAMD who were treated with IVT-AFL in routine clinical practice (FAS, LOCF). ( a ) Mean BCVA over 24 months. Mean BCVA data are reported based on the nearest VA assessments within monthly ± 15-day-visit windows. ( b ) BCVA (letters) from baseline to Month 12 and Month 24. Error bars denote SD. 1 FAS completers were defined as patients with valid visual acuity assessments at baseline and at Month 12 (360 ± 60 days). BCVA: best-corrected visual acuity; CI: confidence interval; ETDRS: Early Treatment Diabetic Retinopathy Study; FAS: full analysis set; IVT-AFL: intravitreal aflibercept; LOCF: last observation carried forward; nAMD: neovascular age-related macular degeneration; SD: standard deviation; VA: visual acuity.
Article Snippet: Figure S1: Mean change in BCVA from baseline to Month 12 and Month 24 following IVT-AFL treatment in treatment-naïve patients with nAMD compared to baseline BCVA (FAS, LOCF); Figure S2: Mean change in CST measured by OCT (μm) from baseline to Month 12 and Month 24 in patients with treatment-naïve nAMD (FAS, LOCF); Table S1: Ethics approval boards; Table S2: Mean change in CST measured by OCT (μm) from baseline to Month 12 and Month 24 in patients with treatment-naïve nAMD (FAS, LOCF); Table S3: Safety overview culminated over 2 years (SAS).
Techniques: Standard Deviation